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Normal hemoglobin (HbA) consists of two alpha-globin and two beta-globin chains. HbA2, consisting of 2 alpha-globin and 2 delta-globin chains, is found in small quantities (3% or less) in normal people, and at higher percentages in people with sickle cell disease. The four subunit composition of HbA and HbA2 describe what level of protein structure?
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