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Many of the working class people in the North were not enthusiastic about freeing the slaves because they would

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NAME: Metformin (Glucophage)MOA: Decreases hepatic glucose production, decreases intestinal absorption of glucose and improves insulin sensitivity (increases peripheral glucose uptake and utilizationClinical: First-line treatment of T2DM, prevention of T2DM in individuals with pre-diabetesADME: onset is days with maximum effect in about 2 weeks, high Vd due to partitioning into liver, kidney, and GI tract, 90% excreted unchanged in urine, CONTRAINDICATED in renal failure (GFR < 70)AE: Gastrointestinal (most common, titrate to desired dose slowly, take with food, GI discomfort essens over several weeks, XR may reduce GI effects), malabsorption of vitamin B12 and folate, metallic taste, lactic acidosis with renal insufficiency (rare)Contraindications: Absolute contraindications: severe renal impairment (GFR < 30 ml/min/1.73 m2), known metformin hypersensitivity, acute or chronic metabolic acidosis, including diabetic ketoacidosis (treat DKA with insulin)Relative contraindications: 30 < GFR < 45 30 ml/min/1.73 m2, pause metformin for 48 hours following radiology with contrast, alcoholic patients, patients with severe hepatic impairmentInteractions: Alcohol, others. Check for drug interactions

How did (most?) U.S. citizens feel about Japan and Japanese people after the attack on Pearl Harbor?

A researcher claims that a certain herbicide suppresses plant growth by inhibiting chloroplast function. To test the claim, the researcher treats isolated chloroplasts with increasing concentrations of the herbicide. The data from the experiment are presented in Table 1.Herbicide Concentration (μg/L) pH Difference across Thylakoid Membrane ATP Production0 3.5 Very high2 2.5 Moderate8 0.5 Very low32 0 Very lowWhich of the following statements best clarifies how the data support the researcher's claim?

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