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Chapter 86. Alcohol withdrawal syndrome occurs when an individual with a dependence on alcohol suddenly limits or stop his or her consumption of alcohol. Nervous symptoms of withdrawal include seizures and uncontrollable shaking of the extremities. What is the most plausible mechanism of action for these physical symptoms?(A) Chronic alcohol consumption causes down-regulation of GABA receptors, leading to a reduction in CNS inhibition, and excito-neurotoxicity.(B) Long-term alcohol abuse stimulates the autonomic nervous system, causing tremors. (C) Cessation of alcohol consumption leads to a reduction in dopamine production in the nucleus accumbens.(D) Alcohol is hallucinogenic, and withdrawal causes the body to respond by relaxing disinhibiting, and amplifying sensory information. (E) Alcohol is a depressant, decreasing inhibitory GABA-binding activity in the central nervous system.
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