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Cefepime is an antibiotic and its side effects include stomach cramps and vomiting. The figure shows the plasma concentration of cefepime following a single i.v. dose in patients with infections and different levels of renal function. The more severe the renal insufficiency (measured by creatinine clearance), the slower the cefepime clearance. Give a plausible clinical consequence for a patient with renal failure following an i.v. dose of cefepime.
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