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Aminolevulinate dehydratase (ALAD) is an enzyme that relies on zinc as a coenzyme. A zinc ion binds to the ALAD active site, where it forms favorable interactions with the side chains of three amino acids. Researchers have found that substituting a lead ion for a zinc ion in the ALAD active site causes inhibition of ALAD.Which of the following statements best helps explain how the lead ion causes inhibition of ALAD?
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