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A 26-year-old woman with a known history of AIDS presents to the ED for strange behavior, according to her boyfriend. Reportedly, she complained of a headache for a few days prior and then began acting bizarrely. In the ED, she has a temperature of 38.5°C (101.3°F). Neurological examination is remarkable for word-finding difficulties accompanied by episodes of clanging and echolalia, along with decreased attention span, recall, and consolidation. A contrast CT scan of the brain reveals multiple ring-enhancing lesions without evidence of midline shift. Which of the following is the most appropriate next step in management?AConsult neurosurgery for a brain biopsyBObtain an MRICTreat with dexamethasoneDTreat with pyrimethamine and sulfadiazineETreat with trimethoprim-sulfamethoxazole
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