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2,3-Diphosphoglycerate (2,3-DPG) concentration increases a lot during exposure to altitude (low ambient PO2). when ambient PO2 is very low, the change in 2,3-DPG can be:a. good because it improves O2 unloading to the tissuesb. bad because it makes O2 unloading more difficult c. good because more O2 binds to Hgb in the lungsd. bad because less O2 binds to Hgb in the lungs
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